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Rac1 and Rac3 GTPases differently influence the morphological maturation of dendritic spines in hippocampal neurons

The Rac1 and Rac3 GTPases are co-expressed in the developing nervous system, where they are involved in different aspects of neuronal development, including the formation of synapses. The deletion of both Rac genes determines a stronger reduction of dendritic spines in vitro compared to the knockout...

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Detalles Bibliográficos
Autores principales: Pennucci, Roberta, Gucciardi, Irene, de Curtis, Ivan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6675090/
https://www.ncbi.nlm.nih.gov/pubmed/31369617
http://dx.doi.org/10.1371/journal.pone.0220496