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Rac1 and Rac3 GTPases differently influence the morphological maturation of dendritic spines in hippocampal neurons
The Rac1 and Rac3 GTPases are co-expressed in the developing nervous system, where they are involved in different aspects of neuronal development, including the formation of synapses. The deletion of both Rac genes determines a stronger reduction of dendritic spines in vitro compared to the knockout...
Autores principales: | Pennucci, Roberta, Gucciardi, Irene, de Curtis, Ivan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6675090/ https://www.ncbi.nlm.nih.gov/pubmed/31369617 http://dx.doi.org/10.1371/journal.pone.0220496 |
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