Stabilization of primary cilia reduces abortive cell cycle re-entry to protect injured adult CNS neurons from apoptosis

Abortive cell cycle (ACC) re-entry of apoptotic neurons is a recently characterized phenomenon that occurs after central nervous system (CNS) injury or over the course of CNS disease. Consequently, inhibiting cell cycle progression is neuroprotective in numerous CNS pathology models. Primary cilia a...

Descripción completa

Detalles Bibliográficos
Autores principales: Choi, Brian K. A., D’Onofrio, Philippe M., Shabanzadeh, Alireza P., Koeberle, Paulo D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6675095/
https://www.ncbi.nlm.nih.gov/pubmed/31369591
http://dx.doi.org/10.1371/journal.pone.0220056

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6675095/
https://www.ncbi.nlm.nih.gov/pubmed/31369591
http://dx.doi.org/10.1371/journal.pone.0220056

Ejemplares similares