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Stabilization of primary cilia reduces abortive cell cycle re-entry to protect injured adult CNS neurons from apoptosis
Abortive cell cycle (ACC) re-entry of apoptotic neurons is a recently characterized phenomenon that occurs after central nervous system (CNS) injury or over the course of CNS disease. Consequently, inhibiting cell cycle progression is neuroprotective in numerous CNS pathology models. Primary cilia a...
Autores principales: | Choi, Brian K. A., D’Onofrio, Philippe M., Shabanzadeh, Alireza P., Koeberle, Paulo D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6675095/ https://www.ncbi.nlm.nih.gov/pubmed/31369591 http://dx.doi.org/10.1371/journal.pone.0220056 |
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