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Episodic evolution of a eukaryotic NADK repertoire of ancient provenance

NAD kinase (NADK) is the sole enzyme that phosphorylates nicotinamide adenine dinucleotide (NAD+/NADH) into NADP+/NADPH, which provides the chemical reducing power in anabolic (biosynthetic) pathways. While prokaryotes typically encode a single NADK, eukaryotes encode multiple NADKs. How these diffe...

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Detalles Bibliográficos
Autores principales: Vickman, Oliver, Erives, Albert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6675116/
https://www.ncbi.nlm.nih.gov/pubmed/31369599
http://dx.doi.org/10.1371/journal.pone.0220447