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The Airn lncRNA does not require any DNA elements within its locus to silence distant imprinted genes

Long non-coding (lnc) RNAs are numerous and found throughout the mammalian genome, and many are thought to be involved in the regulation of gene expression. However, the majority remain relatively uncharacterised and of uncertain function making the use of model systems to uncover their mode of acti...

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Detalles Bibliográficos
Autores principales: Andergassen, Daniel, Muckenhuber, Markus, Bammer, Philipp C., Kulinski, Tomasz M., Theussl, Hans-Christian, Shimizu, Takahiko, Penninger, Josef M., Pauler, Florian M., Hudson, Quanah J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6675118/
https://www.ncbi.nlm.nih.gov/pubmed/31329595
http://dx.doi.org/10.1371/journal.pgen.1008268