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Targeting a highly repeated germline DNA sequence for improved real-time PCR-based detection of Ascaris infection in human stool

BACKGROUND: With the expansion of soil transmitted helminth (STH) intervention efforts and the corresponding decline in infection prevalence, there is an increased need for sensitive and specific STH diagnostic assays. Previously, through next generation sequencing (NGS)-based identification and tar...

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Detalles Bibliográficos
Autores principales: Pilotte, Nils, Maasch, Jacqueline R. M. A., Easton, Alice V., Dahlstrom, Eric, Nutman, Thomas B., Williams, Steven A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6675119/
https://www.ncbi.nlm.nih.gov/pubmed/31329586
http://dx.doi.org/10.1371/journal.pntd.0007593