Cargando…

Lymph node migratory dendritic cells modulate HIV-1 transcription through PD-1 engagement

T-follicular helper (Tfh) cells, co-expressing PD-1 and TIGIT, serve as a major cell reservoir for HIV-1 and are responsible for active and persistent HIV-1 transcription after prolonged antiretroviral therapy (ART). However, the precise mechanisms regulating HIV-1 transcription in lymph nodes (LNs)...

Descripción completa

Detalles Bibliográficos
Autores principales: Banga, Riddhima, Rebecchini, Caterina, Procopio, Francesco Andrea, Noto, Alessandra, Munoz, Olivia, Ioannidou, Kalliopi, Fenwick, Craig, Ohmiti, Khalid, Cavassini, Matthias, Corpataux, Jean-Marc, de Leval, Laurence, Pantaleo, Giuseppe, Perreau, Matthieu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6675123/
https://www.ncbi.nlm.nih.gov/pubmed/31329640
http://dx.doi.org/10.1371/journal.ppat.1007918