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Per-sample immunoglobulin germline inference from B cell receptor deep sequencing data
The collection of immunoglobulin genes in an individual’s germline, which gives rise to B cell receptors via recombination, is known to vary significantly across individuals. In humans, for example, each individual has only a fraction of the several hundred known V alleles. Furthermore, the currentl...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6675132/ https://www.ncbi.nlm.nih.gov/pubmed/31329576 http://dx.doi.org/10.1371/journal.pcbi.1007133 |