Toll-like receptor 4 deficiency or inhibition does not modulate survival and neurofunctional outcome in a murine model of cardiac arrest and resuscitation

BACKGROUND: Patients experiencing cardiac arrest (CA) and cardiopulmonary resuscitation (CPR) often die or suffer from severe neurological impairment. Post resuscitation syndrome is characterized by a systemic inflammatory response. Toll-like receptor 4 (TLR4) is a major mediator of inflammation and...

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Detalles Bibliográficos
Autores principales: Bergt, Stefan, Grub, Andrea, Mueller, Melanie, Bajorat, Rika, Barilar, Ivan, Vollmar, Brigitte, Roesner, Jan Patrick, Wagner, Nana-Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6675321/
https://www.ncbi.nlm.nih.gov/pubmed/31369614
http://dx.doi.org/10.1371/journal.pone.0220404

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6675321/
https://www.ncbi.nlm.nih.gov/pubmed/31369614
http://dx.doi.org/10.1371/journal.pone.0220404

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