Glial S100A6 Degrades β-amyloid Aggregation through Targeting Competition with Zinc Ions

Evidence has been accumulating that zinc ions can trigger β-amyloid (Aβ) deposition and senile plaque formation in the brain, a pathological hallmark of Alzheimer’s disease (AD). Chelating zinc inhibits Aβ aggregation and may hold promise as a therapeutic strategy for AD. S100A6 is an acidic Ca(2+)/...

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Detalles Bibliográficos
Autores principales: Tian, Zhi-Ying, Wang, Chun-Yan, Wang, Tao, Li, Yan-Chun, Wang, Zhan-You
Formato: Online Artículo Texto
Lenguaje:English
Publicado: JKL International LLC 2019
Materias:
Orginal Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6675528/
https://www.ncbi.nlm.nih.gov/pubmed/31440382
http://dx.doi.org/10.14336/AD.2018.0912

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6675528/
https://www.ncbi.nlm.nih.gov/pubmed/31440382
http://dx.doi.org/10.14336/AD.2018.0912

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