Targeted ultra-deep sequencing of a South African Bantu-speaking cohort to comprehensively map and characterize common and novel variants in 65 pharmacologically-related genes

BACKGROUND: African populations are characterised by high genetic diversity, which provides opportunities for discovering and elucidating novel variants of clinical importance, especially those affecting therapeutic outcome. Significantly more knowledge is however needed before such populations can...

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Detalles Bibliográficos
Autores principales: Tshabalala, Sibongile, Choudhury, Ananyo, Beeton-Kempen, Natasha, Martinson, Neil, Ramsay, Michèle, Mancama, Dalu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6675649/
https://www.ncbi.nlm.nih.gov/pubmed/31162291
http://dx.doi.org/10.1097/FPC.0000000000000380

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6675649/
https://www.ncbi.nlm.nih.gov/pubmed/31162291
http://dx.doi.org/10.1097/FPC.0000000000000380

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