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The immunostimulatory effects and pro‐apoptotic activity of rhCNB against Lewis lung cancer is mediated by Toll‐like receptor 4

BACKGROUND: Recombinant human calcineurin B subunit (rhCNB) has been shown to be an immune‐stimulatory protein promoting cytokine production and inducing phenotypic maturation of Dendritic cells (DCs). In vivo, it has good antitumor efficacy, and has potential as an antitumor drug. Exogenous rhCNB w...

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Detalles Bibliográficos
Autores principales: Yang, Jinju, Zhang, Hongwei, Zhu, Ziwei, Gao, Yadan, Xiang, Benqiong, Wei, Qun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6675711/
https://www.ncbi.nlm.nih.gov/pubmed/31218844
http://dx.doi.org/10.1002/cam4.2158