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Pectasol‐C Modified Citrus Pectin targets Galectin‐3‐induced STAT3 activation and synergize paclitaxel cytotoxic effect on ovarian cancer spheroids

Here we sought to determine the relationship between STAT3 activity and Galectin‐3 (Gal‐3) and to investigate the cytotoxic effect of PectaSol‐C Modified Citrus Pectin (Pect‐MCP) as a specific competitive inhibitor of Galectin‐3 (Gal‐3) in combination with Paclitaxel (PTX) to kill the ovarian cancer...

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Detalles Bibliográficos
Autores principales: Hossein, Ghamartaj, Halvaei, Sina, Heidarian, Yassaman, Dehghani‐Ghobadi, Zeinab, Hassani, Mina, Hosseini, Homa, Naderi, Nima, Sheikh Hassani, Shahrzad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6675724/
https://www.ncbi.nlm.nih.gov/pubmed/31197964
http://dx.doi.org/10.1002/cam4.2334