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Modulated electro‐hyperthermia induced p53 driven apoptosis and cell cycle arrest additively support doxorubicin chemotherapy of colorectal cancer in vitro

OBJECTIVE: Modulated electro‐hyperthermia (mEHT), a noninvasive complementary treatment of human chemo‐ and radiotherapy, can generate selective ~42°C heat in cancer due to elevated glycolysis (Warburg‐effect) and electric conductivity in malignant tissues. Here we tested the molecular background of...

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Detalles Bibliográficos
Autores principales: Vancsik, Tamas, Forika, Gertrud, Balogh, Andrea, Kiss, Eva, Krenacs, Tibor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6675742/
https://www.ncbi.nlm.nih.gov/pubmed/31183995
http://dx.doi.org/10.1002/cam4.2330