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Biliary tumorigenic effect on hypopharyngeal cells is significantly enhanced by pH reduction

Biliary reflux has been considered a potential risk factor in upper aerodigestive tract malignancies. It is not yet clearly known how pH affects the bile‐induced activation of NF‐κB and its related oncogenic pathway previously linked to hypopharyngeal carcinogenesis. In this study, repetitive applic...

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Detalles Bibliográficos
Autores principales: Doukas, Sotirios G., Cardoso, Bruno, Tower, Jacob I., Vageli, Dimitra P., Sasaki, Clarence T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6675744/
https://www.ncbi.nlm.nih.gov/pubmed/31173474
http://dx.doi.org/10.1002/cam4.2194