Bioinformatic Methods and Bridging of Assay Results for Reliable Tumor Mutational Burden Assessment in Non-Small-Cell Lung Cancer

INTRODUCTION: Tumor mutational burden (TMB) has emerged as a clinically relevant biomarker that may be associated with immune checkpoint inhibitor efficacy. Standardization of TMB measurement is essential for implementing diagnostic tools to guide treatment. OBJECTIVE: Here we describe the in-depth...

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Detalles Bibliográficos
Autores principales: Chang, Han, Sasson, Ariella, Srinivasan, Sujaya, Golhar, Ryan, Greenawalt, Danielle M., Geese, William J., Green, George, Zerba, Kim, Kirov, Stefan, Szustakowski, Joseph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2019
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6675777/
https://www.ncbi.nlm.nih.gov/pubmed/31250328
http://dx.doi.org/10.1007/s40291-019-00408-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6675777/
https://www.ncbi.nlm.nih.gov/pubmed/31250328
http://dx.doi.org/10.1007/s40291-019-00408-y

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