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Bioinformatic Methods and Bridging of Assay Results for Reliable Tumor Mutational Burden Assessment in Non-Small-Cell Lung Cancer

INTRODUCTION: Tumor mutational burden (TMB) has emerged as a clinically relevant biomarker that may be associated with immune checkpoint inhibitor efficacy. Standardization of TMB measurement is essential for implementing diagnostic tools to guide treatment. OBJECTIVE: Here we describe the in-depth...

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Detalles Bibliográficos
Autores principales:	Chang, Han, Sasson, Ariella, Srinivasan, Sujaya, Golhar, Ryan, Greenawalt, Danielle M., Geese, William J., Green, George, Zerba, Kim, Kirov, Stefan, Szustakowski, Joseph
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer International Publishing 2019
Materias:	Original Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6675777/ https://www.ncbi.nlm.nih.gov/pubmed/31250328 http://dx.doi.org/10.1007/s40291-019-00408-y

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