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Monitoring activities of receptor tyrosine kinases using a universal adapter in genetically encoded split TEV assays

Receptor tyrosine kinases (RTKs) play key roles in various aspects of cell biology, including cell-to-cell communication, proliferation and differentiation, survival, and tissue homeostasis, and have been implicated in various diseases including cancer and neurodevelopmental disorders. Ligand-activa...

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Detalles Bibliográficos
Autores principales: Wintgens, Jan P., Wichert, Sven P., Popovic, Luksa, Rossner, Moritz J., Wehr, Michael C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6675780/
https://www.ncbi.nlm.nih.gov/pubmed/30623207
http://dx.doi.org/10.1007/s00018-018-03003-2