Morphine-Induced Modulation of Endolysosomal Iron Mediates Upregulation of Ferritin Heavy Chain in Cortical Neurons

HIV-associated neurocognitive disorders (HAND) remain prevalent and are aggravated by µ-opioid use. We have previously shown that morphine and other µ-opioids may contribute to HAND by inhibiting the homeostatic and neuroprotective chemokine receptor CXCR4 in cortical neurons, and this novel mechani...

Descripción completa

Detalles Bibliográficos
Autores principales: Nash, Bradley, Tarn, Kevin, Irollo, Elena, Luchetta, Jared, Festa, Lindsay, Halcrow, Peter, Datta, Gaurav, Geiger, Jonathan D., Meucci, Olimpia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2019
Materias:
New Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6675873/
https://www.ncbi.nlm.nih.gov/pubmed/31300544
http://dx.doi.org/10.1523/ENEURO.0237-19.2019

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6675873/
https://www.ncbi.nlm.nih.gov/pubmed/31300544
http://dx.doi.org/10.1523/ENEURO.0237-19.2019

Ejemplares similares