Cargando…

A Yeast Suppressor Screen Used To Identify Mammalian SIRT1 as a Proviral Factor for Middle East Respiratory Syndrome Coronavirus Replication

Viral proteins must intimately interact with the host cell machinery during virus replication. Here, we used the yeast Saccharomyces cerevisiae as a system to identify novel functional interactions between viral proteins and eukaryotic cells. Our work demonstrates that when the Middle East respirato...

Descripción completa

Detalles Bibliográficos
Autores principales: Weston, Stuart, Matthews, Krystal L., Lent, Rachel, Vlk, Alexandra, Haupt, Rob, Kingsbury, Tami, Frieman, Matthew B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6675885/
https://www.ncbi.nlm.nih.gov/pubmed/31142674
http://dx.doi.org/10.1128/JVI.00197-19