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Temporal Proteomic Analysis of BK Polyomavirus Infection Reveals Virus-Induced G(2) Arrest and Highly Effective Evasion of Innate Immune Sensing

BK polyomavirus (BKPyV) is a small DNA virus that establishes a life-long persistent infection in the urinary tract of most people. BKPyV is known to cause severe morbidity in renal transplant recipients and can lead to graft rejection. The simple 5.2-kbp double-stranded DNA (dsDNA) genome expresses...

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Detalles Bibliográficos
Autores principales: Caller, Laura G., Davies, Colin T. R., Antrobus, Robin, Lehner, Paul J., Weekes, Michael P., Crump, Colin M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6675895/
https://www.ncbi.nlm.nih.gov/pubmed/31142673
http://dx.doi.org/10.1128/JVI.00595-19