AsiDNA Treatment Induces Cumulative Antitumor Efficacy with a Low Probability of Acquired Resistance()()

The Achilles heel of anticancer treatments is intrinsic or acquired resistance. Among many targeted therapies, the DNA repair inhibitors show limited efficacy due to rapid emergence of resistance. We examined evolution of cancer cells and tumors treated with AsiDNA, a new DNA repair inhibitor target...

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Detalles Bibliográficos
Autores principales: Jdey, Wael, Kozlak, Maria, Alekseev, Sergey, Thierry, Sylvain, Lascaux, Pauline, Girard, Pierre-Marie, Bono, Françoise, Dutreix, Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2019
Materias:
Original article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6675950/
https://www.ncbi.nlm.nih.gov/pubmed/31362243
http://dx.doi.org/10.1016/j.neo.2019.06.006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6675950/
https://www.ncbi.nlm.nih.gov/pubmed/31362243
http://dx.doi.org/10.1016/j.neo.2019.06.006

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