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The effect of an alternative chromosome 17 probe on fluorescence in situ hybridization for the assessment of HER2 amplification in invasive breast cancer

Fluorescent in situ hybridization (FISH) is commonly used to determine the ratio of human epidermal growth factor receptor 2 (HER2) to centromere enumeration probe for chromosome 17 (CEP17), which further determines HER2 gene status in breast cancer. However, due to copy number alteration in CEP17,...

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Detalles Bibliográficos
Autores principales: Xu, Zhigao, Xu, Peipei, Fan, Wei, Huang, Ben, Cheng, Qingyuan, Zhang, Zheng, Wang, Ping, Yu, Mingxia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6676089/
https://www.ncbi.nlm.nih.gov/pubmed/31410164
http://dx.doi.org/10.3892/etm.2019.7756