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Induced miR‐31 by 5‐fluorouracil exposure contributes to the resistance in colorectal tumors

Drug resistance makes treatment difficult in cancers. The present study identifies and analyzes drug resistance‐related miRNA in colorectal cancer. We established 4 types of 5‐fluorouracil (5‐FU)‐resistant colon cancer cell lines in vitro and in vivo. We then analyzed the miRNA expression profile by...

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Detalles Bibliográficos
Autores principales: Nakagawa, Yoshihito, Kuranaga, Yuki, Tahara, Tomomitsu, Yamashita, Hiromi, Shibata, Tomoyuki, Nagasaka, Mitsuo, Funasaka, Kohei, Ohmiya, Naoki, Akao, Yukihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6676105/
https://www.ncbi.nlm.nih.gov/pubmed/31162779
http://dx.doi.org/10.1111/cas.14090