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Interleukin‐6 production mediated by the IRE1‐XBP1 pathway confers radioresistance in human papillomavirus‐negative oropharyngeal carcinoma

Endoplasmic reticulum stress (ERS) plays a key role in the pathogenesis and development of tumors and protects tumor cells from radiation damage and drug‐induced stress. We previously demonstrated that EGFR confers radioresistance in human papillomavirus (HPV)‐negative human oropharyngeal carcinoma...

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Detalles Bibliográficos
Autores principales: Lyu, Xintong, Zhang, Miao, Li, Guangqi, Cai, Yiru, Li, Guang, Qiao, Qiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6676107/
https://www.ncbi.nlm.nih.gov/pubmed/31187548
http://dx.doi.org/10.1111/cas.14094