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Targeting PIN1 exerts potent antitumor activity in pancreatic ductal carcinoma via inhibiting tumor metastasis

The human prolyl isomerase PIN1, best known for its association with carcinogenesis, has recently been indicated in the disease of pancreatic ductal adenocarcinoma (PDAC). However, the functions of PIN1 and the feasibility of targeting PIN1 in PDAC remain elusive. For this purpose, we examined the e...

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Detalles Bibliográficos
Autores principales: Chen, Linying, Xu, Xiao, Wen, Xinxin, Xu, Shenmin, Wang, Long, Lu, Wenxian, Jiang, Mingting, Huang, Jing, Yang, Dayun, Wang, Jichuang, Zheng, Min, Zhou, Xiao Zhen, Lu, Kun Ping, Liu, Hekun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6676117/
https://www.ncbi.nlm.nih.gov/pubmed/31148345
http://dx.doi.org/10.1111/cas.14085