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PC-1 NF suppresses high glucose-stimulated inflammation and extracellular matrix accumulation in glomerular mesangial cells via the Wnt/β-catenin signaling

Diabetic nephropathy (DN) is the leading cause of end-stage renal disease worldwide with high morbidity and mortality. Glomerular mesangial cell (MC) proliferation, inflammatory cell infiltration and extracellular matrix (ECM) accumulation are the main pathological characteristics of DN. A previous...

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Detalles Bibliográficos
Autores principales: Xiao, Liangxiang, Chen, Yingying, Yuan, Yang, Xu, Bo, Gao, Qing, Chen, Ping, Zhang, Tianying, Guan, Tianjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6676197/
https://www.ncbi.nlm.nih.gov/pubmed/31410160
http://dx.doi.org/10.3892/etm.2019.7793