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Morphine and HIV-1 gp120 cooperatively promote pathogenesis in the spinal pain neural circuit

Opioids are common analgesics for pain relief in HIV patients. Ironically, emerging clinical data indicate that repeated use of opioid analgesics in fact leads to a heightened chronic pain state. To understand the underlying pathogenic mechanism, we generated a mouse model to study the interactive e...

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Detalles Bibliográficos
Autores principales: Shi, Yuqiang, Yuan, Subo, Tang, Shao-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6676262/
https://www.ncbi.nlm.nih.gov/pubmed/31368399
http://dx.doi.org/10.1177/1744806919868380