BRD4 inhibitor and histone deacetylase inhibitor synergistically inhibit the proliferation of gallbladder cancer in vitro and in vivo

Gallbladder cancer (GBC) is the most common malignancy of the bile duct and has a high mortality rate. Here, we demonstrated that BRD4 inhibitor JQ1 and histone deacetylase inhibitor suberoylanilide hydroxamic acid (SAHA) synergistically inhibited the GBC cells in vitro and in vivo. Our results show...

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Detalles Bibliográficos
Autores principales: Liu, Shilei, Li, Fengnan, Pan, Lijia, Yang, Ziyi, Shu, Yijun, Lv, Wenjie, Dong, Ping, Gong, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6676267/
https://www.ncbi.nlm.nih.gov/pubmed/31215139
http://dx.doi.org/10.1111/cas.14102

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6676267/
https://www.ncbi.nlm.nih.gov/pubmed/31215139
http://dx.doi.org/10.1111/cas.14102

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