Exosomal microRNAs derived from colon cancer cells promote tumor progression by suppressing fibroblast TP53 expression

The tumor microenvironment offers favorable conditions for tumor progression, and activated fibroblasts, known as cancer‐associated fibroblasts, play a pivotal role. TP53‐deficient cancer cells are known to induce strong fibroblast activation. We aimed to elucidate the oncogenic role of exosomes der...

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Detalles Bibliográficos
Autores principales: Yoshii, Shunsuke, Hayashi, Yoshito, Iijima, Hideki, Inoue, Takanori, Kimura, Keiichi, Sakatani, Akihiko, Nagai, Kengo, Fujinaga, Tetsuji, Hiyama, Satoshi, Kodama, Takahiro, Shinzaki, Shinichiro, Tsujii, Yoshiki, Watabe, Kenji, Takehara, Tetsuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6676271/
https://www.ncbi.nlm.nih.gov/pubmed/31148360
http://dx.doi.org/10.1111/cas.14084

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6676271/
https://www.ncbi.nlm.nih.gov/pubmed/31148360
http://dx.doi.org/10.1111/cas.14084

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