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Imaging individual protein aggregates to follow aggregation and determine the role of aggregates in neurodegenerative disease
Protein aggregates play a key role in the initiation and spreading of neurodegenerative disease but have been difficult to study due to their low abundance and heterogeneity, in both size and structure. Fluorescence based methods capable of detecting and characterising single aggregates have recentl...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6676340/ https://www.ncbi.nlm.nih.gov/pubmed/30611780 http://dx.doi.org/10.1016/j.bbapap.2018.12.010 |