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The effects of increased acetate turnover on glucose-induced insulin secretion in lean and obese humans

INTRODUCTION: Increased endogenous acetate production (Ra) in rodents has been shown to activate the parasympathetic nervous system and thereby promote increased glucose-stimulated insulin secretion (GSIS), increased ghrelin secretion, hyperphagia and obesity. AIM: To examine whether rates of acetat...

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Detalles Bibliográficos
Autores principales: Petersen, Kitt Falk, Impellizeri, Anne, Cline, Gary W., Shulman, Gerald I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6676497/
https://www.ncbi.nlm.nih.gov/pubmed/31404159
http://dx.doi.org/10.1017/cts.2018.342