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Stability and flexibility in chromatin structure and transcription underlies memory CD8 T-cell differentiation
The process by which naïve CD8 T cells become activated, accumulate, and terminally differentiate as well as develop into memory cytotoxic T lymphocytes (CTLs) is central to the development of potent and durable immunity to intracellular infections and tumors. In this review, we discuss recent studi...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
F1000 Research Limited
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6676507/ https://www.ncbi.nlm.nih.gov/pubmed/31448086 http://dx.doi.org/10.12688/f1000research.18211.1 |