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Stability and flexibility in chromatin structure and transcription underlies memory CD8 T-cell differentiation

The process by which naïve CD8 T cells become activated, accumulate, and terminally differentiate as well as develop into memory cytotoxic T lymphocytes (CTLs) is central to the development of potent and durable immunity to intracellular infections and tumors. In this review, we discuss recent studi...

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Detalles Bibliográficos
Autores principales: Diao, Huitian, Pipkin, Matthew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6676507/
https://www.ncbi.nlm.nih.gov/pubmed/31448086
http://dx.doi.org/10.12688/f1000research.18211.1