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Mesenchymal stromal cell-derived nanovesicles ameliorate bacterial outer membrane vesicle-induced sepsis via IL-10

BACKGROUND: Sepsis remains a source of high mortality in hospitalized patients despite proper antibiotic approaches. Encouragingly, mesenchymal stromal cells (MSCs) and their produced extracellular vesicles (EVs) have been shown to elicit anti-inflammatory effects in multiple inflammatory conditions...

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Detalles Bibliográficos
Autores principales: Park, Kyong-Su, Svennerholm, Kristina, Shelke, Ganesh V., Bandeira, Elga, Lässer, Cecilia, Jang, Su Chul, Chandode, Rakesh, Gribonika, Inta, Lötvall, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6676541/
https://www.ncbi.nlm.nih.gov/pubmed/31370884
http://dx.doi.org/10.1186/s13287-019-1352-4