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Constructing treatment selection rules based on an estimated treatment effect function: different approaches to take stochastic uncertainty into account have a substantial effect on performance

BACKGROUND: Today we are often interested in the predictive value of a continuous marker with respect to the expected difference in outcome between a new treatment and a standard treatment. We can investigate this in a randomized control trial, allowing us to assess interactions between treatment an...

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Detalles Bibliográficos
Autores principales: Eckert, Maren, Vach, Werner
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6676573/
https://www.ncbi.nlm.nih.gov/pubmed/31370791
http://dx.doi.org/10.1186/s12874-019-0805-x