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When to keep it simple – adaptive designs are not always useful

BACKGROUND: Adaptive designs are a wide class of methods focused on improving the power, efficiency and participant benefit of clinical trials. They do this through allowing information gathered during the trial to be used to make changes in a statistically robust manner – the changes could include...

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Detalles Bibliográficos
Autores principales: Wason, James M. S., Brocklehurst, Peter, Yap, Christina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6676635/
https://www.ncbi.nlm.nih.gov/pubmed/31370839
http://dx.doi.org/10.1186/s12916-019-1391-9