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Helical and kinase domain mutations of PIK3CA, and their association with hormone receptor expression in breast cancer

Breast cancer is one of the major causes of female morbidity and mortality, accounting for ~25% of the total cancer cases in women. Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic α subunit (PIK3CA) mutations serve a major role in downstream signaling of receptor tyrosine kinases. The prese...

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Detalles Bibliográficos
Autores principales: Vatte, Chittibabu, Al Amri, Ali Mohammed, Cyrus, Cyril, Chathoth, Shahanas, Alsayyah, Ahmed, Ahmad, Arafat, Akhtar, Mohammed Shakil, Alrashidi, Nada Fehaid, Jayaseeli, Nithya, Al Wadani, Hamed, Al Zahrani, Alhussain, Al Ali, Amein Kadhem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6676675/
https://www.ncbi.nlm.nih.gov/pubmed/31404155
http://dx.doi.org/10.3892/ol.2019.10565