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Mechanistic Studies of Idiosyncratic DILI: Clinical Implications

The idiosyncratic nature of idiosyncratic drug-induced liver injury (IDILI) makes mechanistic studies very difficult, and little is known with certainty. However, the fact that the IDILI caused by some drugs is associated with specific HLA genotypes provides strong evidence that it is mediated by th...

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Detalles Bibliográficos
Autor principal: Uetrecht, Jack
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6676790/
https://www.ncbi.nlm.nih.gov/pubmed/31402866
http://dx.doi.org/10.3389/fphar.2019.00837