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Mechanistic Studies of Idiosyncratic DILI: Clinical Implications
The idiosyncratic nature of idiosyncratic drug-induced liver injury (IDILI) makes mechanistic studies very difficult, and little is known with certainty. However, the fact that the IDILI caused by some drugs is associated with specific HLA genotypes provides strong evidence that it is mediated by th...
Autor principal: | Uetrecht, Jack |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6676790/ https://www.ncbi.nlm.nih.gov/pubmed/31402866 http://dx.doi.org/10.3389/fphar.2019.00837 |
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