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Contribution of acrB upregulation & OmpC/Ompk36 loss over the presence of bla(NDM) towards carbapenem resistance development among pathogenic Escherichia coli & Klebsiella spp.

BACKGROUND & OBJECTIVES: The global spread of carbapenem-resistant Enterobacteriaceae (CRE) is an emerging clinical problem. Hence, in this study, the plausible role of extended-spectrum beta-lactamases (ESBLs)/carbapenemases, OmpC/Ompk36, acrB and their combinations was explored among CRE. METH...

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Detalles Bibliográficos
Autores principales: Pal, Arijit, Dhara, Lena, Tripathi, Anusri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6676854/
https://www.ncbi.nlm.nih.gov/pubmed/31411177
http://dx.doi.org/10.4103/ijmr.IJMR_716_17