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Meox2 Haploinsufficiency Accelerates Axonal Degeneration in DBA/2J Glaucoma

PURPOSE: Glaucoma is a complex disease with major risk factors including advancing age and increased intraocular pressure (IOP). Dissecting these earliest events will likely identify new avenues for therapeutics. Previously, we performed transcriptional profiling in DBA/2J (D2) mice, a widely used m...

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Detalles Bibliográficos
Autores principales: Buchanan, Rebecca A., Foley, Kate E., Pepper, Keating W., Reagan, Alaina M., Keezer, Kelly J., Hewes, Amanda A., Diemler, Cory A., Preuss, Christoph, Soto, Ileana, John, Simon W. M., Howell, Gareth R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6676925/
https://www.ncbi.nlm.nih.gov/pubmed/31369031
http://dx.doi.org/10.1167/iovs.18-26126