Biochemical and structural explorations of α-hydroxyacid oxidases reveal a four-electron oxidative decarboxylation reaction

p-Hydroxymandelate oxidase (Hmo) is a flavin mononucleotide (FMN)-dependent enzyme that oxidizes mandelate to benzoylformate. How the FMN-dependent oxidation is executed by Hmo remains unclear at the molecular level. A continuum of snapshots from crystal structures of Hmo and its mutants in complex...

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Detalles Bibliográficos
Autores principales: Yeh, Hsien-Wei, Lin, Kuan-Hung, Lyu, Syue-Yi, Li, Yi-Shan, Huang, Chun-Man, Wang, Yung-Lin, Shih, Hao-Wei, Hsu, Ning-Shian, Wu, Chang-Jer, Li, Tsung-Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2019
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6677016/
https://www.ncbi.nlm.nih.gov/pubmed/31373572
http://dx.doi.org/10.1107/S2059798319009574

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6677016/
https://www.ncbi.nlm.nih.gov/pubmed/31373572
http://dx.doi.org/10.1107/S2059798319009574

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