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Conformational diversity induces nanosecond-timescale chemical disorder in the HIV-1 protease reaction pathway
The role of conformational diversity in enzyme catalysis has been a matter of analysis in recent studies. Pre-organization of the active site has been pointed out as the major source for enzymes' catalytic power. Following this line of thought, it is becoming clear that specific, instantaneous,...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Royal Society of Chemistry
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6677113/ https://www.ncbi.nlm.nih.gov/pubmed/31588289 http://dx.doi.org/10.1039/c9sc01464k |