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Intervention changes acoustic peak frequency and mesolimbic neurochemistry in the Pink1-/- rat model of Parkinson disease

The neural mechanisms underlying behavioral therapy for vocal acoustic deficits in patients with Parkinson disease is unknown. A primary hypothesis is that voice therapy may modulate mesolimbic brainstem regions, including the ventral tegmental area (VTA). The VTA is implicated in ultrasonic call pe...

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Detalles Bibliográficos
Autores principales: Stevenson, Sharon A., Ciucci, Michelle R., Kelm-Nelson, Cynthia A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6677310/
https://www.ncbi.nlm.nih.gov/pubmed/31374106
http://dx.doi.org/10.1371/journal.pone.0220734