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The right ventricular fibroblast secretome drives cardiomyocyte dedifferentiation

RATIONALE: In virtually all models of heart failure, prognosis is determined by right ventricular (RV) function; thus, understanding the cellular mechanisms contributing to RV dysfunction is critical. Whole organ remodeling is associated with cell-specific changes, including cardiomyocyte dedifferen...

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Detalles Bibliográficos
Autores principales: Bruns, Danielle R., Tatman, Philip D., Kalkur, Roshni S., Brown, R. Dale, Stenmark, Kurt R., Buttrick, Peter M., Walker, Lori A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6677314/
https://www.ncbi.nlm.nih.gov/pubmed/31374110
http://dx.doi.org/10.1371/journal.pone.0220573