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The right ventricular fibroblast secretome drives cardiomyocyte dedifferentiation
RATIONALE: In virtually all models of heart failure, prognosis is determined by right ventricular (RV) function; thus, understanding the cellular mechanisms contributing to RV dysfunction is critical. Whole organ remodeling is associated with cell-specific changes, including cardiomyocyte dedifferen...
Autores principales: | Bruns, Danielle R., Tatman, Philip D., Kalkur, Roshni S., Brown, R. Dale, Stenmark, Kurt R., Buttrick, Peter M., Walker, Lori A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6677314/ https://www.ncbi.nlm.nih.gov/pubmed/31374110 http://dx.doi.org/10.1371/journal.pone.0220573 |
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