Dafachronic acid promotes larval development in Haemonchus contortus by modulating dauer signalling and lipid metabolism

Here, we discovered an endogenous dafachronic acid (DA) in the socioeconomically important parasitic nematode Haemonchus contortus. We demonstrate that DA promotes larval exsheathment and development in this nematode via a relatively conserved nuclear hormone receptor (DAF-12). This stimulatory effe...

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Detalles Bibliográficos
Autores principales: Ma, Guangxu, Wang, Tao, Korhonen, Pasi K., Young, Neil D., Nie, Shuai, Ang, Ching-Seng, Williamson, Nicholas A., Reid, Gavin E., Gasser, Robin B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6677322/
https://www.ncbi.nlm.nih.gov/pubmed/31335899
http://dx.doi.org/10.1371/journal.ppat.1007960

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6677322/
https://www.ncbi.nlm.nih.gov/pubmed/31335899
http://dx.doi.org/10.1371/journal.ppat.1007960

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