Cargando…

piRNA-guided co-transcriptional silencing coopts nuclear export factors

The PIWI-interacting RNA (piRNA) pathway is a small RNA-based immune system that controls the expression of transposons and maintains genome integrity in animal gonads. In Drosophila, piRNA-guided silencing is achieved, in part, via co-transcriptional repression of transposons by Piwi. This depends...

Descripción completa

Detalles Bibliográficos
Autores principales: Fabry, Martin H, Ciabrelli, Filippo, Munafò, Marzia, Eastwood, Evelyn L, Kneuss, Emma, Falciatori, Ilaria, Falconio, Federica A, Hannon, Gregory J, Czech, Benjamin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6677536/
https://www.ncbi.nlm.nih.gov/pubmed/31219034
http://dx.doi.org/10.7554/eLife.47999