KDM2A-dependent reduction of rRNA transcription on glucose starvation requires HP1 in cells, including triple-negative breast cancer cells

Triple-negative breast cancer (TNBC) is very aggressive and lacks specific therapeutic targets. Ribosome RNAs (rRNAs) are central components of ribosomes and transcribed in nucleoli, and the level of rRNA transcription greatly affects ribosome production and cell proliferation. We have reported that...

Descripción completa

Detalles Bibliográficos
Autores principales: Okamoto, Kengo, Tanaka, Yuji, Ogasawara, Sachiko, Obuse, Chikashi, Nakayama, Jun-ichi, Yano, Hirohisa, Tsuneoka, Makoto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6677663/
https://www.ncbi.nlm.nih.gov/pubmed/31413816
http://dx.doi.org/10.18632/oncotarget.27092

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6677663/
https://www.ncbi.nlm.nih.gov/pubmed/31413816
http://dx.doi.org/10.18632/oncotarget.27092

Ejemplares similares